The Sage™ test
The Sage™ test
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The Sage™ prenatal screen test report gives a clear, easy to interpret result of high or low risk. All high risk results must receive further investigation to exclude a false-positive result.

Low risk: it is very unlikely that the pregnancy is affected by a trisomy or aneuploidy.

High risk: the pregnancy is at increased risk for trisomy or aneuploidy and the result should be confirmed through further investigation which may involve an invasive procedure such as amniocentesis.

No result: very occasionally there is insufficient placental DNA in the sample to obtain a result and a re-draw may be required at no additional cost.

Individual reports are produced depending on the aneuploidies requested.

A sample trisomy Sage™ prenatal test screening report is available for download here.

A sample SCA Sage™ prenatal test screening report is available for download here.

A sample microdeletions Sage™ prenatal test screening report is available for download here.

Fetal Fraction

The Sage™ prenatal screen analyses and reports the amount of fetal cfDNA circulating in the maternal blood stream and reports this as fetal fraction. Some pregnant women may have too little fetal (placental) DNA available for analysis which is reported as "low fetal fraction". There may be several reasons for this. For instance, women with a high maternal weight may have increased blood volume which could result in a dilution of the cell-free placental DNA in the maternal plasma. The Sage™ prenatal screen incorporates clever bioinformatics software that is able to produce valid and accurate results in samples that have as little as 3.5% fetal fraction.