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Infectious Disease
Clarigene RUO
Clarigene CE-IVD
Clarigene SARS-CoV-2 CE-IVD
Clarigene™ Feature Notes
NIPT
IONA® Nx
For Clinical Laboratories
Overview
Workflow
Clinical Performance
Benefits of the IONA® Nx NIPT Workflow
Instruments
IONA® Software
Atlas Workflow Manager
MyNIPT®
Technical Support
Quality and Regulatory
Choose IONA® Nx NIPT Workflow
the IONA® test
For Clinical Laboratories
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Technology
CE-IVD
Clinical Performance
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MyNIPT®
Application Support
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Laboratory Customer Login
For Pregnant Women
Overview
What is NIPT?
How does it work?
Performance Characteristics
Who can have the IONA® Test
Results
Where can I get the IONA® test?
UK & Ireland Locations
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For Healthcare Professionals
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MyNIPT®
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Responsible Screening
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Sage™ Prenatal Screen
For Clinical Laboratories
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Choose Sage™
Sage QS 32plex
For Pregnant Women
Advantages of the Sage™ prenatal screen
Overview
Who can have the Sage™ test
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For Healthcare Professionals
Overview
Background
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Reproductive Health
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Rapid Aneuploidy Analysis
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Precision Medicine
Elucigene DPYD
DPYD Overview
DPYD Testing Workflow
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Yourgene Flex™
Platforms
Yourgene® QS250
Yourgene® SP150

The IONA® Nx NIPT Workflow (IONA® Nx) is Yourgene Health’s non-invasive prenatal test (NIPT) that runs on the Illumina NGS platform.

A fully validated workflow that utilises next generation sequencing (NGS) and has been developed to run on Illumina’s NextSeq 550Dx instrument.

IONA® Nx, is a screening test that performs:

  • Whole genome analysis to measure the likelihood that a pregnant woman is carrying a fetus with:

Most common trisomies 

Trisomy 21 (Down’ Syndrome) 

Trisomy 18 (Edwards’ Syndrome) 

Trisomy 13 (Patau’s Syndrome) 

Autosomal Aneuploidies (AAs)

Additional trisomy across the whole-genome

All monosomy across the whole-genome

Sex Chromosome Aneuploidies (SCAs)

45,X (Turner Syndrome) 

47,XXX (Trisomy X) 

47,XXY (Klinefelter’s Syndrome) 

47,XYY (Jacob’s Syndrome)

  • Fetal Sex Determination

 

Key Features of the IONA® Nx NIPT Workflow

  • Advanced proprietary reagents and software technologies
  • Simple process with minimum instrumentation capital expenditure, suppliers and contract services
  • Designed to offer flexibility (automated or manual) and scalability to suit varying customer needs

overview