fbpx
Image is not available
Expertise  / Partnership / Comprehensive
Image is not available
Expertise  / Partnership / Comprehensive
Image is not available
Expertise  / Partnership / Comprehensive
previous arrow
next arrow
Slider

Test performance observed following validation metrics for singleton and twin pregnancies

IONA® Nx validation studya
 SensitivitySpecificity
Trisomy 21

100%
(46/46)
95% CI: 92.3 - 100%

100% 
(426/426)
95% CI: 98.14 – 100%

Trisomy 18

100%
(20/20)
95% CI: 83.2 – 100%

99.19%
(452/452)
95% CI: 99.19 – 100%

Trisomy 13

100%
(10/10)
95% CI: 69.2 – 100%

100%
(462/462)
95% CI: 99.2 – 100%

a The Validation performance has been demonstrated by evaluating 472 clinical samples from singleton and twin pregnancy and comparing to a reference result of an amniocentesis or chorionic villus sampling (CVS) sample or a birth outcome.

This has been demonstrated using the IONA® Nx cfDNA Library Preparation DX kit and the IONA® analysis software version 2.0.2. Data held on file by Yourgene Health Plc.