Yourgene provides three complementary screening solutions to meet more of our lab customers', clinicians' and pregnant women's needs across different international locations.
The IONA® Nx NIPT Workflow is a CE marked in vitro (IVD) for prenatal screening which enables clinical laboratories around the world to establish their own quality assured non-invasive prenatal screening service. This test is registered as a regulated IVD in many different regions. Yourgene Genomic Services use the IONA® Nx NIPT Workflow in the Manchester laboratory to offer a quality NIPT testing service.
The IONA® test was the first CE marked (IVD) for prenatal screening which also allows clinical laboratories to establish their own quality assured non-invasive prenatal screening service. The IONA® test is registered as a regulated IVD in many different regions.
The Sage™ prenatal screen is available in additional regions where a regulated NIPT is not required for trisomy screening. Sage™ provides highly accurate screening results for a greater clinical depth of chromosomal conditions including trisomies, sex chromosomal aneuploidies, autosomal aneuploidies and some select microdeletions. The Sage™ prenatal screen is available as a service from Yourgene Genomic Services in Taipei.|
Feature |
IONA® Nx NIPT Workflow (CE-IVD) [with the Illumina NextSeq 550Dx] |
The IONA® test (CE-IVD) [with the Thermo Fisher Ion Torrent Systems] |
Sage™ prenatal screen [with the Thermo Fisher Ion Torrent Systems] |
|
Clinical content: |
Comprehensive whole-genome analysis |
Comprehensive whole-genome analysis |
Comprehensive whole-genome analysis |
|
Trisomy 21, 18, 13 |
✔ |
✔ |
✔ |
|
Sex chromosomal aneuploidies (SCAs) – optional |
✔ |
✔ |
✔ |
|
Autosomal aneuploidies (AAs) – optional |
✔ |
✔ |
✔ |
|
Microdeletions – optional |
Coming soon in 2021 |
x |
✔ |
|
CNVs |
Coming soon in 2021 |
x |
x |
|
Fetal sex determination – optional |
✔ |
✔ |
✔ |
|
CE-IVD |
✔ |
✔ |
x |
|
Suitable for low to high throughput laboratories |
✔ |
✔ |
✔ |
|
Fully automated workflow with workflow manager for full sample traceability |
✔ |
✔ |
x |
|
NIPT service available from Yourgene Genomic Services (Manchester, UK and Taipei,Taiwan) |
✔ |
x |
✔ |
|
MyNIPT® sample tracking and reporting portal |
✔ |
✔ |
x |
|
Minimum fetal fraction required using proprietary dynamic method |
≥2% |
≥2% |
≥3.5% |
|
Installation, complete training and technical support (from 3 weeks) |
✔ |
✔ |
✔ |
|
|
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Click for further information on the IONA® Nx NIPT Workflow, the IONA® test and the Sage™ prenatal screen.